I credit Andy Clarke with the idea of improving the approach of working with wireframes by using the Grey Box Method. I highly recommend his book, Trancending CSS, for both the fantastic content and beautiful design.
I love the idea of changing the process of developing web sites to be content-driven rather than design-driven. And I’m saying that as a designer. Of course, design has a huge part to play, but content is the critical piece of the site. Without it, the design is pointless.